Vitamins & Supplements

Can You Take Vitamin B12 With Other Vitamins & Supplements?

Vitabiotics | Published: 03/02/2026

Can You Take Vitamin B12 With Other Vitamins & Supplements? Can You Take Vitamin B12 With Other Vitamins & Supplements?

Vitamin B12 is often linked with the reduction of tiredness and fatigue, so it’s natural to wonder how it fits alongside other vitamins in your routine. If you’ve been asking “can you take B12 with other vitamins?”, this guide walks you through the most common combinations.

A balanced diet should always come first, yet supplements can be a helpful way to support your intake during busy periods or particular life stages. If you’re unsure about your nutritional needs, it’s a good idea to speak to a health professional.

What is vitamin B12 and its benefits?

Vitamin B12 (also known as cobalamin) is a water-soluble vitamin that belongs to the family of eight essential B vitamins. The good news is that they’re found in a variety of foods including whole grains, meats, nuts, seeds, eggs and dark green leafy vegetables.

You can explore our full range of vitamin B12 supplements, or read more about what is vitamin B12 and the benefits of vitamin B12 on our site.

Vitamin B12 contributes to:

  • Normal energy release
  • The reduction of tiredness and fatigue
  • Normal psychological function
  • Normal red blood cell formation
  • Normal function of the immune system
  • Normal functioning of the nervous system
  • Normal homocysteine metabolism

Additionally, vitamin B12 has a role in the process of cell division.

These roles help explain why B12 is included across many multivitamins and energy release-supporting formulations.

Taking vitamin B12 with other vitamins and supplements

Many people combine vitamin B12 with other nutrients as part of a daily wellness routine. Most pairings work well together, although one or two may be better taken at different times to support absorption. Below, we take each common combination in turn.

Can you take vitamin D and vitamin B12 together?

Vitamin D and B12 are commonly taken together and are frequently found in the same multivitamin. They each play different roles in the body, so they don’t compete for absorption. Vitamin D contributes to the normal function of the immune system and helps support normal bones and muscle function. Vitamin B12 contributes to normal energy release and the reduction of tiredness and fatigue.

If you follow a plant-based diet, you may find this combination particularly helpful, as both nutrients can be harder to obtain from foods alone.

Explore our vitamin D range.

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Can you take vitamin B12 and iron together?

Vitamin B12 and iron are often included in the same supplement because they both play a role in red blood cells. Iron contributes to normal oxygen transport in the body and to the normal formation of haemoglobin, while vitamin B12 contributes to normal red blood cell formation.

These nutrients can be safely taken together.

Browse our iron supplements.

Can you take vitamin B12 and magnesium together?

Magnesium and vitamin B12 can be taken together without concern, as both Magnesium and vitamin B12 contribute to a reduction of tiredness and fatigue. Magnesium also contributes to normal muscle function and normal psychological function. They do not interfere with one another’s absorption.

Discover our magnesium range.

Can you take vitamin B12 and vitamin C together?

You can safely take vitamin B12 and vitamin C together. Vitamin C contributes to normal collagen formation to the normal function of skin, bones, cartilage and blood vessels, and should be consumed regularly as part of aa healthy balanced diet as it is not stored in large amounts in the body.

Take a look at our vitamin C supplement range to support any gaps in your diet.

Can you take folic acid and vitamin B12 together?

Folic acid (vitamin B9) and B12 are often taken together, both in daily multivitamins and in life-stage supplements. They both contribute to the reduction of tiredness and fatigue, and they also contribute to normal function of the immune system.

These nutrients are frequently combined in supplements because vitamin B12 is needed for the body to use folate. There are no known negative interactions.

Explore our folic acid supplement range.

Can you take vitamin B complex with B12?

Yes, you can take a vitamin B complex with vitamin B12. A B complex supplement includes all eight B vitamins, including B12 and vitamin B6. Many people also ask can you take vitamin B12 and B6 together, as B6 is another nutrient commonly included in these formulas.

Because B vitamins are water soluble and available in a wide range of strengths, some people choose to tailor their intake depending on their routine or preferences. For example, someone may take a multivitamin and still decide to add a B complex, or include additional vitamin B12, based on what feels right for them.

Browse our vitamin B supplements range.

Can you take vitamin B12 and Omega-3 together?

There’s no interaction between Omega-3 and vitamin B12, and they are often used alongside each other. Omega-3 supplements typically provide DHA and EPA, which contribute to the normal function of the heart, while DHA alone contributes to the maintenance of normal brain function with a daily intake of 250mg DHA, and maternal intake of DHA contributes to normal foetal brain and eye development (with a daily intake of 200mg DHA in addition to the recommended daily intake of Omega-3 fatty acids for adults).

Discover our omega-3 supplements.

Can you take ashwagandha with vitamin B12?

Ashwagandha and vitamin B12 can be taken together. Ashwagandha can help to support relaxation as well as mental and physical wellbeing, while vitamin B12 contributes to normal psychological function.

Explore our ashwagandha supplement here.

Can you take vitamin B12 with a multivitamin?

Many multivitamins already include vitamin B12, as they’re designed to provide a broad range of nutrients in balanced amounts, making them a convenient option if you prefer everything in one tablet. Some people may still choose to take additional vitamin B12 alongside a multivitamin, depending on their individual circumstances. As everyone’s needs are different, it’s a good idea to speak to a health professional if you’re considering combining supplements.

Take a look at our multivitamins range.

Final thoughts

Taking vitamin B12 with other vitamins and supplements is generally considered safe, and many combinations fit naturally into a daily wellness routine. If you’ve been wondering “can you take B12 with other vitamins?”, the answer is usually yes, as long as you’re choosing supplements that suit your lifestyle and nutritional needs. It’s always worth speaking to a health professional if you have questions about how different nutrients might work together.

Finding a simple, sustainable approach is what matters most. When you’ve got a routine that suits you, vitamin B12 can sit alongside your other nutrients with ease.

Meet the Author

El Berwick

El Berwick

Copywriter

El Berwick

Copywriter

El Berwick is a copywriter and editor with 20 years’ experience, specialising in health, wellness, and human (and pet!) supplements. Once a frequent travel writer, she now finds plenty of adventure at home with her two young kids and leaf-chasing spaniel. 

Reviewed By

Melissa Cohen

Melissa Cohen

BSc (Hons), Head of Nutrition & Training

Melissa Cohen

BSc (Hons), Head of Nutrition & Training

Melissa Cohen is a leading nutritional therapist with over 17 years of experience helping people optimise their health. Over 10 years as a senior lecturer at the Naturopathic College of Medicine, Melisa developed her expertise in teaching and mentoring, while also sharing her insights on women’s health for educational audiences. Today, she leads the nutrition and training team at Vitabiotics, bringing her clinical, teaching, and communication experience together to deliver evidence-based nutrition education to both health professionals and learners.

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